Active Pharmaceutical Ingredients (API) Market

Active Pharmaceutical Ingredients (API) Market Size, Share & Trends Analysis Report

Active Pharmaceutical Ingredients (API) Market By Product (Standalone DPI, Integrated DPI), By Application (Government, Internet Service Provider, Enterprises, Education, Others), Industry Analysis, Trends, And Forecast, 2022-2028

Report ID : BMRC 51
Number of pages : 300
Published Date : Apr 2023
Category : Pharmaceutical
Delivery Timeline : 48 hrs

Active Pharmaceutical Ingredients Market is valued at USD 184.2 Billion in 2020 and is expected to reach USD 284.4 Billion by 2027 with a CAGR of 6.4% over the forecast period.         

Global Active Pharmaceutical Ingredients (API) Market: Global Size, Trends, Competitive, Historical & Forecast Analysis, 2022-2028- Rising prevalence of chronic diseases, increasing geriatric population and growing R&D in the anti-viral drug are some of the major factors anticipated to drive the Growth the API Market.

Scope of Active Pharmaceutical Ingredients Market:

Active pharmaceutical ingredient (API) is the name utilized to mention to the biologically active component of a drug product that is a capsule, tablet. Mostly, drug products are included with various components. The active pharmaceutical ingredient is one of the primary ingredients. These substances which make up a variable fraction of the drug product are essential to be biologically safe. The process for optimizing and composting the combination of components utilized in the drug is known as formulation. Active pharmaceutical ingredients are utilized for pharmacological activity in the diagnosis, treat, mitigation, treatment, or prevention of disease or to change the structure or function of the body.

There are two types of active pharmaceutical ingredients which are chemical synthetic drugs (usually produced by contract manufacturing outsourcing) and natural chemical drugs. The production of active pharmaceutical ingredients is exceptionally difficult. It includes a series of responses like blend to accomplish a specific change in the chemical design from short-sighted looking molecules. The high temperature and pressing factor control tasks of the reactions which are utilized in the formulations of these active pharmaceutical ingredients which include raw materials which are exceptionally flammable make it a cycle full of complexities and risks. The applications of API’s are lower risk of drug interaction, increased understanding of the drug and its action, increased compliance from the patient better acceptance of the drug’s side effects and symptoms.

COVID-19 pandemic has also impacted the global API Market. To relieve the indications and the different health conditions which a patient of COVID-19 appearances, like high fever, cough, and cold different sorts of medications are utilized thus the pharmaceutical business become the center of the globe during the pandemic. During COVID-19 pandemic, the economic and social burden has provoked government bodies to expand funding for vaccine advancement on a worldwide scale. This has prompted a rise in the development of the active pharmaceutical ingredients (API) market. However, the pharmaceuticals production and supply chain both got disturbed during lockdown. Due to the lockdowns conditions, slow production of APIs by the later resulted in less accessibility and higher costs for the materials required for generics invention.

API Manufacturers:

Some of the key players in global active pharmaceutical ingredient market are Sun Pharmaceutical Industries Ltd.

  • Mylan NV
  • Pfizer Inc.
  • Sanofi SA
  • Novartis International AG
  • Teva Pharmaceutical Industries Ltd.
  • Merck & Co. Inc.
  • Eli Lilly and Company
  • AstraZeneca PLC
  • Bayer AG
  • Hoffmann-La Roche Ltd.
  • Sun pharmaceutical industries
  • Apex Healthcare Ltd.
  • Aurobindo Pharma
  • Ipca laboratories limited
  • dr.Pharmaceuticals Limited
  • marksans pharma

API Market Segmentation:

Global active pharmaceutical ingredients market is segmented on the basis of business type, synthesis, drug type, application and region & country level. Based upon business type, the global active pharmaceutical ingredients market is classified into captive API and merchant API. Based upon API type, the market is classified into synthetic API, biotech API and other. Based upon drug type, the global active pharmaceutical ingredients market is classified into generic and branded. Based upon application, the market is classified into pain management, respiratory diseases, orthopaedic disorder, neurological disorder, diabetes, oncology, urology and other.

By Business Mode:

  • Captive API
  • Merchant APIs

By Synthesis:

  • Synthetic API
  • Biotech API
  • Other

By Drug Type:

  • Generic
  • Branded

By Application:

  • Pain Management
  • Respiratory Diseases
  • Orthopedic Disorder
  • Neurological Disorder
  • Diabetes
  • Oncology
  • Urology
  • Other

The regions covered in global API Industry are North America, Europe, Asia-Pacific, Latin America and Rest of the World. On the basis of country level, the market of global active pharmaceutical ingredients is sub divided into U.S., Mexico, Canada, U.K., France, Germany, Italy, China, India, Japan, South East Asia, Middle East Asia (UAE, Egypt, Saudi Arabia) GCC, Africa, etc.


MEDISCA Launched New Thyroid API - Now Available to Compounding Pharmacists after Years of Industry-Wide Disruptions to Supply

On August 26th, 2021; MEDISCA officially started accepting orders for its long-awaited thyroid active pharmaceutical ingredient (thyroid API), making a predictable supply for intensifying drug specialists, prescribers and obviously, their patients. For the past few years, the intensifying community has battled to discover consistent stock of thyroid API. MEDISCA saw the great need and cooperated with Sichuan Deebio Pharmaceutical Company (Deebio), one of the universes' driving manufacturers of pharmaceutical APIs and one of a handful of the producers who can separate thyroid hormones. Until now, MEDISCA has popularized thyroid API in the United States in compounding and non- compounding enterprises.

Rising Prevalence of Chronic Diseases, Increasing Geriatric Population and Growing R&D in Anti-Viral Drug are Some of the Major Factors Driving the Market Growth

One of the major factors driving the growth of global API Industry is rising prevalence of chronic diseases. Rising number of chronic diseases such as diabetic, cardiovascular diseases, cancer and other is increasing the demand of drugs which leads to foster the growth of the global active pharmaceutical ingredients market. For example; as per the International Diabetes Federation, in 2019, 463 million individuals across the world were determined to have diabetes. In addition, the quantity of new cancer cases each year is relied upon to increment to 23.6 million by 2030. In addition, the increasing geriatric population is also supplementing the market growth.

For instance, as per the World Health Organization (WHO), there were 703 million individuals aged 65 or more worldwide in 2019. Furthermore, growing R&D in anti-viral drugs also drives the global active pharmaceutical ingredients market. New drug developments and improvements boost the development of the global active pharmaceutical ingredients market. For instance; as per the American Chemical Society in 2019, there has been 48 new medications has been endorsed by the FDA U.S. out of which 11 new cancer treatments with inventive molecular pharmaceutical ingredients.

However, high manufacturing cost may hamper the growth of the global active pharmaceutical ingredients market. In spite of that, a rise in the production of biosimilars, which are generic version of the patented drug, can provide various opportunities for the further growth of the global active pharmaceutical ingredients market.

North America is Expected to Dominate the Global Active Pharmaceutical Ingredients Market

North America is expected to dominate the global API Industry due to the increasing chronic diseases & other diseases, rising R&D activities and presence of key players in this region. For instance; according to the Centers for Disease Control and Prevention; around 795,000 individuals in the U.S. experience the ill effects of stroke each year, out of which 87% cases are of ischemic stroke. Rise in research and development programs in drugs & medical science is also supplementing the market growth in this region. For example, in 2020, Pfizer signed a multi-year arrangement with Gilead Sciences to make and supply Gilead's antiviral medication (Remdesivir) for the treatment of COVID-19.

Asia Pacific is expected to witness the fastest growth in this market during the forecast period due to the increasing healthcare expenditure and large number of pharmaceutical companies. For instance; in December 2019, Dr Reddy's Laboratories dispatched Bortezomib for infusion in the US market, a conventional variant of Velcade of Millennium Pharmaceuticals. Bortezomib is utilized for the treatment of adult patients with various myeloma or with mantle cell lymphoma who have received somewhere around one earlier treatment.

On Special Requirement API Industry Report is also available for the below Regions and Country:

North America

  • U.S.
  • Canada


  • Germany
  • France
  • U.K.
  • Italy
  • Spain
  • Sweden
  • Netherland
  • Turkey
  • Switzerland
  • Belgium
  • Rest of Europe


  • South Korea
  • Japan
  • China
  • India
  • Australia
  • Philippines
  • Singapore
  • Malaysia
  • Thailand
  • Indonesia
  • Rest Of APAC

Latin America

  • Mexico
  • Colombia
  • Brazil
  • Argentina
  • Peru
  • Rest of South America

Middle East and Africa

  • Saudi Arabia
  • UAE
  • Egypt
  • South Africa

Report Analysis


Historical data

2015 - 2020

Forecast Period

2021 - 2027

Market Size in 2020:

USD 184.2 Billion 

Base year considered


Forecast Period CAGR %:


Market Size Expected in 2027:

USD 284.4 Billion 

Tables, Charts & Figures:




API manufacturers

Mylan NV, Pfizer Inc., Sanofi SA, Novartis International AG, Teva Pharmaceutical Industries Ltd., Merck & Co. Inc., Eli Lilly and Company,  AstraZeneca PLC, Bayer AG, Hoffmann-La Roche Ltd., Sun pharmaceutical industries, Apex Healthcare Ltd.,  Aurobindo Pharma, Ipca laboratories limited dr., Pharmaceuticals limited marksans pharma.

Segments Covered

By Business Mode, By Synthesis, By Drug Type, By Application

Regional Analysis

North America, U.S., Mexico, Canada, Europe, UK, France, Germany, Italy, Asia Pacific, China, Japan, India, Southeast Asia, South America, Brazil, Argentina, Columbia, The Middle East and Africa, GCC, Africa, Rest of the Middle East and Africa

Key Benefits of API Industry Report-

  • Global Active Pharmaceutical Ingredients trends report covers in-depth historical and forecast analysis.
  • Global Active Pharmaceutical Ingredients Market industry statistics research report provides detailed information about Market Introduction, Market Summary, Global market Revenue (Revenue USD), Market Drivers, Market Restraints, Market opportunities, Competitive Analysis, Regional and Country Level.
  • Global Active Pharmaceutical Ingredients Market industry analysis report helps to identify opportunities in the market place.
  • Global Active Pharmaceutical Ingredients trends report covers extensive analysis of emerging trends and competitive landscape.
  • Global API Market report covers all API manufacturers Of MEA