Gene Cloning Services Market

Industry Insights-

• The Global Gene Cloning Services Market was valued at USD 2386.1 Million in 2021
• It is anticipated to reach USD 6620.3 Million by 2028
• A CAGR of 18.54% is anticipated over the forecast period

Market Overview-

Gene cloning is a typical practice in molecular biology labs that is utilized by specialists to make duplicates of a specific gene for downstream applications like mutagenesis, sequencing, genotyping, or heterologous articulation of a protein. The conventional technique for gene cloning includes the exchange of a DNA fragment of interest from one organism to a self-reproducing genetic component, like a bacterial plasmid. This method is regularly involved in isolating long or unstudied genes and protein articulation. A more recent strategy is the utilization of polymerase chain reaction (PCR) for enhancing a gene of interest.

Covid-19 Impact-

The COVID-19 pandemic had a positive impact on the growth of the global gene cloning services market. Ongoing research and development for the COVID-19 vaccine has fueled the growth of the gene cloning services market. Outbreaks of the COVID-19 epidemic have rapidly increased the research activities in gene cloning services. However, as decision-makers moved their priorities to Coronavirus related issues, which impacted the market's growth.

Key Players-

Some of the key players for global Gene Cloning Services Market are

• Charles River Laboratories
• Bio-Techne
• Eurofins
• GenScript
• Integrated DNA Technologies
• Curia
• Sino Biological
• Twist Bioscience
• MedGenome
• Cellecta Inc.
• Thermo Fisher Scientific Inc.
• GenScript
• Takara Bio Inc.
• Lonza
• Sartorius AG
• Synbio Technologies
• Dobuss (Canvax)
• Azenta US Inc.
• Macrogen Inc.
• Codex DNA Inc.
• Eurofins
• Scientific
• Creative Biogene
• TransGen Biotech Co. Ltd.
• Bio-Rad
• Syngene
• Takara Bio Inc.
• Lonza

Segmentation Analysis-

By Service:

• Custom Cloning Service
• Molecular Biology Service
• Gene Synthesis Service
• Others

On the basis of service, the global gene cloning service market is segmented into custom cloning services, molecular biology services, gene synthesis services, and others. The custom cloning segment is projected to experience a rapid growth during the forecast period, primarily due to the increasing demand for gene custom cloning services. The rising demand for customized cloning services in the biological and medical fields, coupled with the increasing prevalence of infectious and chronic diseases, is expected to drive the market during the forecast period. Moreover, the penetration of synergistic services and the ability to analyze the impact of mutation on a specific gene and the production of proteins using biomedical methods are some of the other factors expected to have a positive impact on the market's growth.

By Application:

• Gene Therapy
• Vaccine Research
• Gene Expression
• Gene Synthesis
• Others

By application, the global gene cloning service market is segmented into gene therapy, vaccine research, gene expression, gene synthesis, and others. The gene synthesis segment is expected to grow substantially over the forecast period. This growth is attributed to the rising prevalence of genetic diseases, increasing investments in genomics research, and the development of new sequencing technologies. Furthermore, the growing demand for personalized medicine and the increasing demand for high-throughput sequencing are expected to fuel the market's growth. Additionally, government initiatives to promote the use of genetic testing and the increasing application of DNA sequencing in cancer research are expected to propel the market's growth.

By End-User:

• Clinical Laboratories
• Pharmaceutical & Biotechnology Companies
• Others

By end-user, the market is segmented into clinical laboratories, pharmaceutical and biotechnology companies, and others. The emergence of gene cloning services is expected to be a boon for pharmaceutical and biotechnology companies. These services are fast, accurate, and provide the desired constructs, freeing up the end-users to focus on other important research steps. This will likely drive the demand for DNA and gene cloning services in the next five years, as the biomedical field continues to rapidly evolve.

By Regional & Country Level:

• North America

  • U.S.
  • Canada

• Europe

  • U.K.
  • France
  • Germany
  • Italy

• Asia Pacific

  • China
  • Japan
  • India
  • Southeast Asia

• Latin America

  • Brazil
  • Mexico

• Middle East and Africa

  • GCC
  • Africa
  • Rest of Middle East and Africa 

North America is holding a major share in the global gene cloning services market within the forecast period due to rising chronic diseases, technological advancement, and presence of key players. For instance, according to the American Cancer Society, in 2022, there will be an expected 1.9 million new cancer cases analyzed and 609,360 malignant growth deaths in the U.S. Also, the presence of key players drives the market in the North America region over the forecast period. Numerous key players in the region provides new revenue streams, consequently it is supporting the growth of the market into the region. For example, in January 2021, Codex DNA and Pfizer signed an early access collaboration and licensing agreement, which will permit Pfizer to involve CodexDNA's original enzymatic DNA licensing agreement in its research & development of mRNA-based vaccines and biotherapies. Codex DNA will be held accountable for furthering innovation.

The Asia Pacific is holding a major share in the global gene cloning services market due to increasing research & development activities and rising disposable income in the region. For example, in May 2020, Takara Bio announced a joint effort with AGC Biologics. The organizations will team up on a prophylactic DNA vaccine against Coronavirus, with AGC Biologics producing the plasmid DNA intermediate for the vaccine.

Market Drivers

Increasing chronic and infectious diseases

One of the major factors that supporting the growth of the global gene cloning services market is the increasing chronic and infectious diseases. Cloning can be utilized to deliver gene treatments for the therapy of serious disease signs like cancer, cystic fibrosis, AIDS, and others. Likewise, gene cloning is utilized for the making of insulin and human growth hormones. Furthermore, their use in gene therapy to treat or avoid illness by correcting the fundamental hereditary issue is influencing market interest.

The different applications of gene cloning in the biomedical field are supposed to fuel the worldwide gene cloning services market interest over the forecast period. For example, according to the World Health Organization (WHO), cardiovascular diseases represent most NCD deaths, or 17.9 million individuals yearly, trailed by cancers at around 9.3 million individuals, chronic respiratory diseases at around 4.1 million individuals, and diabetes at around 2.0 million individuals, including kidney infection deaths brought about by diabetes.

Growing advancement in technology in cloning and sub-cloning service

In addition, the growing advancement in technology in cloning and sub-cloning services is boosting the growth of the global gene cloning services market. For instance, in May 2020, GenScript launched a GMP single-strand and double-strand DNA service to help with the development of gene and cell treatments. The declaration features GenScript's commitment to helping whole non-viral cell treatment advancement through the IND-empowering and clinical stages. However, the complications related to large-scale production of cloning vectors may hamper the growth of the global gene cloning services market. In spite of that, the increasing demand for gene & cloning services can provide some opportunity in the global gene cloning services market.

Recent Developments-

• On May 16th, 2022; GenScript USA, Inc. has made new GMP-grade GenExactTM single-stranded DNA (ssDNA) and GenWandTM closed-end linear double-stranded DNA (dsDNA) services available. These services will empower next-generation gene and cell treatment research and development projects to progress to IND filing and clinical preliminaries quicker and all the more productively. CRISPR-based non-viral gene insertion techniques have acquired prevalence among research groups with worries about the FDA's new draught guidance concerning the utilization of viruses for gene and cell treatment. Non-viral HDR templates, in combination with CRISPR innovation, can speed up cell engineering compared with conventional GMP virus-based engineering, conveying results quicker than substitute techniques.

Report Analysis	Details
Historical data	2016 - 2021
Forecast Period	2022 - 2029
Market Size in 2021:	USD 2386.1 Million
Base year considered	2021
Forecast Period CAGR %:	18.54%
Market Size Expected in 2028:	USD 6620.3 Million
Tables, Charts & Figures:	175
Pages	300
Gene Cloning Services Companies	Charles River Laboratories, Bio-Techne,Eurofins,GenScript,Integrated DNA Technologies,Curia,Sino Biological,Twist Bioscience,MedGenome,Cellecta, Inc.,Thermo Fisher Scientific Inc.,GenScript,Takara Bio Inc.,Lonza,Sartorius AG,Synbio Technologies,Dobuss (Canvax),Azenta US, Inc.,Macrogen, Inc.,Codex DNA Inc.,Eurofins, Scientific,Creative Biogene,TransGen Biotech Co., Ltd.,Bio-Rad, Syngene, Takara Bio Inc.,Lonza.,
Segments Covered	By Service, By Gene Type, By Application, By End-User
Regional Analysis	North America, U.S., Mexico, Canada, Europe, UK, France, Germany, Italy, Asia Pacific, China, Japan, India, Southeast Asia, South America, Brazil, Argentina, Columbia, The Middle East and Africa, GCC, Africa, Rest of the Middle East and Africa