Global Bovine Blood Plasma Derivatives Market: Global Size, Trends, Competitive, and Historical & Forecast Analysis, 2024-2030: The market is poised for expansion fueled by cutting-edge biotechnology innovations, ongoing research breakthroughs, and rising demand for biopharmaceuticals like thrombin. These factors promise dynamic growth opportunities, driving forward the development and adoption of advanced medical solutions worldwide.
Global Bovine Blood Plasma Derivatives Market is valued at USD 3.1 Billion in 2023 and it is expected to generate absolute dollar opportunity of USD 4.7 Billion by 2030.
Bovine plasma is the liquid component of cattle blood that remains after the removal of red blood cells, white blood cells, and platelets. This yellowish fluid constitutes about 55% of the total blood volume and acts as a medium for transporting nutrients, hormones, proteins, and waste products throughout the body.
Bovine blood plasma derivatives are products obtained from the plasma of cattle blood that have been processed to isolate specific components for various applications. The derivatives of bovine blood plasma are immunoglobulin, fibrinogen, Bovin serum albumin, fetal Bovin serum, newborn calf serum, thrombin and other derivatives.
These derivatives find diverse applications across pharmaceuticals, biotechnology, and the food industry. They are crucial for therapies treating immune deficiencies and coagulation disorders. In biotechnology, these derivatives are utilized in diagnostics, research, and regenerative medicine. Additionally, they are used for their nutritional benefits in functional foods, dietary supplements, and animal feed, supporting growth and health in livestock and companion animals. Their wide-ranging applications underscore their significance in various sectors requiring high-quality protein-based products with therapeutic and nutritional value.
The COVID-19 pandemic had a mixed impact on the global bovine blood plasma derivatives market, highlighting both vulnerabilities and opportunities. While the industry faced significant challenges, it also adapted by accelerating research, enhancing supply chain resilience, and exploring new applications. The pandemic caused interruptions in the supply of raw materials, including bovine blood, due to restrictions on livestock farming and transport. Many processing plants faced shutdowns or operated at reduced capacity due to lockdown measures and workforce shortages.
However, there was an increased demand for bovine blood plasma derivatives for research and development of COVID-19 treatments and vaccines. This spike in demand was driven by the urgent need to find effective solutions to combat the virus.
Some of the prominent players in the global bovine blood plasma derivatives market are Proliant Health & Biologicals, PlasmaGen, Thermo Fischer Scientific, Merk, Sera Care, TCS Biosciences, Bovogen Biologicals, Rocky Mountain Biologicals, Bio Rad, Cytiva, R&D Systems, Moregate BioTech, Gemini, Bovogen, Biowest, RMBIO, VWR, Corning, Zhejiang Tianhang Biotechnology, Sonac, Ex Cell Bio and others.
(June 9, 2023) Proliant Health & Biologicals, a leading manufacturer of Bovine Serum Albumin (BSA), and LAMPIRE Biological Laboratories, a global provider of biopharmaceutical and diagnostic testing products, announced a strategic partnership. The partnership between Proliant Health & Biologicals and LAMPIRE Biological Laboratories signifies a shared commitment to providing high-quality products and exceptional service to customers worldwide. Lampire leverages its expertise in contract filling to packaging and distribute Proliant's renowned BSA in smaller package sizes, meeting the specific requirements of customers.
Advancements in biotechnology and research are pivotal in driving the growth of the bovine blood plasma derivatives market. These advancements have significantly enhanced the extraction, purification, and utilization of plasma derivatives, expanding their applications across pharmaceuticals, biotechnology, and the food industry.
In pharmaceuticals, plasma derivatives such as immunoglobulins and coagulation factors are crucial for treating immune deficiencies, hemophilia, and other genetic disorders. For instance, according to the Plasma Protein Therapeutics Association (PPTA), in 2020, plasma protein therapies were used by millions of patients worldwide, highlighting their critical role in healthcare.
Biotechnological advancements have enabled the development of innovative diagnostic tools and therapies using plasma derivatives. Research in regenerative medicine explores the potential of plasma proteins in tissue engineering and wound healing, accelerating healing processes and improving patient outcomes.
Moreover, in the food industry, plasma derivatives are utilized in functional foods, dietary supplements, and animal feed to enhance nutrition and promote health in livestock and companion animals. This supports growth and immune function, addressing global challenges in food security and animal health.
Overall, advancements in biotechnology and ongoing research efforts continue to expand the bovine blood plasma derivatives market, offering new therapeutic avenues and nutritional benefits across diverse sectors worldwide.
The increasing demand for biopharmaceuticals, specifically thrombin derived from bovine blood plasma, is significantly driving the market for plasma derivatives. Thrombin plays a crucial role in hemostasis, the process of blood clot formation, essential for controlling bleeding during surgical procedures and in treating various medical conditions.
Globally, the demand for thrombin is rising due to its widespread use in surgical settings. For instance, thrombin-based hemostats are extensively utilized in cardiovascular, orthopedic, and general surgeries to manage bleeding effectively and accelerate wound healing.
Bovine blood plasma derivatives offer advantages such as high purity, stability, and consistent efficacy, meeting regulatory standards for biopharmaceutical use. They are preferred in biopharmaceutical applications due to their reliability compared to synthetic alternatives. Advances in biotechnology and production processes further enhance the availability and efficacy of thrombin from bovine blood plasma, supporting its growing demand in the biopharmaceutical industry.
Overall, the increasing request for biopharmaceuticals like thrombin underscores the critical role of bovine blood plasma derivatives in modern medicine, driving innovation and market expansion in response to healthcare needs globally.
Zoonotic Disease Concerns: Bovine blood plasma derivatives, sourced from cattle, raise concerns regarding the potential transmission of zoonotic diseases to humans. Despite stringent safety measures and regulatory standards, the perceived risk of diseases such as prion diseases (e.g., Bovine Spongiform Encephalopathy) or viral infections is a significant consideration for regulatory bodies, healthcare providers, and consumers. These concerns may prompt stricter regulations or diminish consumer confidence, potentially affecting market growth.
Alternative Plasma Derivatives: There is increasing interest and development in alternative sources for plasma derivatives that do not involve bovine origins. These alternatives include plasma derived from human donors, recombinant technologies (produced in cell cultures), and other animal species like porcine or avian sources. Advances in biotechnology and production processes are enhancing the feasibility and safety profile of these alternatives, potentially diverting demand away from bovine-derived products.
Rising Demand in Biopharmaceuticals: There is increasing utilization of bovine blood plasma derivatives in biopharmaceutical applications, particularly in therapies for immune deficiencies, coagulation disorders, and wound healing. The development of new therapeutic applications and the expansion into emerging markets offer substantial growth opportunities.
Expanding Applications in Food and Nutritional Supplements: Growing consumer awareness and demand for functional foods and nutritional supplements drive opportunities for incorporating bovine blood plasma derivatives. These derivatives are valued for their high protein content and bioactive components, offering potential in enhancing nutritional formulations.
Technological Advancements in Production: Innovations in biotechnological processes, including recombinant technologies and advanced filtration techniques, enhance the efficiency and safety of producing bovine blood plasma derivatives. Companies investing in scalable production methods and novel extraction technologies can gain competitive advantages.
Incorporating bovine blood plasma derivatives into pet food formulations is a strategy aimed at enhancing the nutritional profile and health benefits of pet foods. Bovine blood plasma derivatives are rich in proteins, peptides, and other bioactive compounds that can contribute to overall pet health. The pet food industry in North America has been expanding due to greater pet ownership rates, increased spending on premium pet food products, and a growing focus on pet health and nutrition.
As of 2024, approximately 66% of U.S. households, which equates to around 86.9 million homes, own at least one pet as per the Forbes. Hence increasing number of pets will drive the market of bovine plasma derivatives as incorporating bovine blood plasma derivatives into pet food formulations is becoming a strategy increasingly used by pet food manufacturers to enhance the nutritional content and health benefits of their products.
In addition, there has been a notable rise in surgical interventions across North America. This increase is driven by advancements in surgical techniques, aging populations requiring more complex procedures, and a greater emphasis on surgical solutions for medical conditions. Thrombin is used in surgical settings for its hemostatic properties. It helps control bleeding during and after surgery, promoting faster wound healing and reducing the risk of complications such as excessive bleeding. As of 2024, according to the Centers for Disease Control and Prevention (CDC), the number of Cesarean deliveries (C-sections) in the United States is reported to be 1,178,066. Hence as the number of surgeries increases there will be an increase in demand of thrombin in turn will spur the bovine blood plasma derivatives market in North America region.
Technological advancements such as key players expanding their facilities can ramp up production capabilities, meeting rising demand more effectively. These investments in technology enable the development of innovative products with improved efficacy, safety, and functionality in bovine blood plasma derivatives. For instance, On April 3, 2022, ANZCO Foods, a New Zealand-based manufacturer and supplier specializing in animal serums, proteins, and plasma, expanded its healthcare capabilities by acquiring Moorgate Biotech, a biotechnology firm. Moorgate Biotech specializes in supplying animal by-products such as sera, proteins, and plasma.
R&D expanding their R&D capabilities to enter new markets or diversify their product portfolios. This strategic expansion helps in tapping into new revenue streams and reducing dependency on specific markets or products. For instance, in May 2023, PlasmaGen Biosciences ('PlasmaGen'), a biopharmaceutical company specializing in blood plasma-derived pharmaceutical products for India and emerging markets, inaugurated its new manufacturing plant for blood plasma-derived protein therapeutics in Kolar, Bengaluru. Covering 8 acres, this advanced facility comprises interconnected, independently operable blocks designed to facilitate diverse stages of the manufacturing process. The establishment of this state-of-the-art facility marks a milestone in enhancing the availability of blood-plasma derived products, aiming to address supply-demand dynamics and make these products more accessible at affordable prices and help the market to grow in Asia Pacific region.
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