Global Natural Killer Cells Therapeutics Market is valued at USD 1.94 Billion in 2020 and is expected to reach USD 5.92 Billion by 2027 with a CAGR of 17.28% over the forecast period.
Global Natural Killer Cells Therapeutics Market: Global Size, Trends, Competitive, Historical & Forecast Analysis, 2020-2027- Factors like increasing prevalence of cancer cases, rising adoption of natural killer cells for the treatment of liver as well as infectious diseases, growing need of effective therapeutics and rising awareness regarding immunotherapy are some of the major factors driving the growth of the market.
Natural killer (NK) cells are lymphocytes of the innate immune system. NK cells constitute the human body’s frontline defense system as they control different types of tumors and microbial infections by inhibiting their spread and tissue damage. NK cells have cytotoxicity against tumor cells. According to a recent research study, NK cell biology has paved the way for new therapeutic strategies based on NK cells for the treatment of various cancers as they can target just the cancerous cells and allow the immune system to kill tumors with minimal side effects. Treatment includes the enhancement of antibody-dependent cellular cytotoxicity, the manipulation of receptor-mediated activation, inclusion criteria based on killer cell immunoglobulin-like receptor legend mismatches, and adoptive immunotherapy with ex vivo expanded chimeric antigen receptor car engineered or modified NK cells. NK cells are expected to be revolutionary cellular medicines for the treatment of malignancies.
Covid-19 has affected the growth of the global natural killer cells therapeutics market. It is majorly used in the treatment of cancer but due to this pandemic situation, many healthcare services have been delayed globally which has affected the global natural killer cells therapeutics market. However, according to the University Of Central Florida (UCF) in October 2020; natural killer cell therapy is in trials for treating COVID-19 as therapy stimulates the body’s natural killer (NK) cells with nanoparticles to increase their numbers and killing ability which may provide an opportunity for its growth in the coming period.
The regions covered in this global NK cells therapeutics market report are North America, Europe, Asia-Pacific, and the Rest of the World. On the basis of country level, the market of global NK cells therapeutics is subdivided into U.S., Mexico, Canada, U.K., France, Germany, Italy, China, Japan, India, South East Asia, Middle East Asia (UAE, Saudi Arabia, Egypt) GCC, Africa, etc.
The major key players of global natural killer cells therapeutics market are Affimed, AltorBioscience Corporation, Celgene, CytoVac, Dynavax, GamidaCell, NantKwest, PersonGen BioTherapeutics, Surface Oncology, ZIOPHARM Oncology, Five Prime Therapeutics Nohla Therapeutics, iCell Gene Therapeutics, Fortress Biotech, Avid Biotic Corporation, Sorrento Therapeutics, Multimmune GmbH, Innate Pharma and others.
The global natural killer cells therapeutics market is segmented on the basis of type, applications end-users, and regional and country level. On the basis of type, the global NK cells therapeutics market is classified into NK cell therapies and Nk cell-directed antibodies. On the basis of disease, the global NK cells therapeutics market is classified into cancer, immune proliferative disorder. On the basis of end-users, the global NK cells therapeutics market is classified into hospitals and research centers.
Factors like an increase in the prevalence of cancer cases, a rise in utilization of natural killer cells for the treatment of liver as well as infectious diseases, and growing awareness of immunotherapy are driving the growth of the market. Increasing cases of cancers are also supplementing the market growth. For example; according to National Cancer Institute; in 2020, 1,806,590 new cancer cases were estimated in the United States. As NK cells have the property to eliminate immunosuppressive immune cells in the tumor, which helps to treat cancer. In addition, there is a number of infectious diseases are spreading all over the world such as chickenpox, HIV AIDS, tuberculosis, Covid-19, measles, and others. For instance; according to WHO, it is estimated that in 2019, 10 million cases of TB worldwide. With 5.6 million men, 3.2 million women, and 1.2 million children Also, According to World Health Organization, in 2021, there are 157,289,118 confirmed cases of covid-19, including 3,277,272 deaths.
These infectious diseases are spreading through bacteria, viruses, fungi, or some parasites. Sometimes these organisms are not harmful but sometimes they might cause deaths. As NK cells have antibacterial effects against intracellular bacterial pathogens which can kill the infected cells. Hence, the rising adoption of natural killer cells for the treatment of liver as well as infectious diseases is also propelling the growth of the market. However, unfavorable effects of NK cells therapeutics may hinder the growth of the global NK cells therapeutics market. In spite of that, investment in research and development by the government or by the different organizations can consequently offer more opportunities for the further growth of the market.
The global natural killer cells therapeutics market is segmented into North America, Europe, Asia-Pacific Latin America, and Middle East & Africa. North America is expected to dominate the global natural killer cells therapeutics market within the forecast period attributed to rising demand for NK cell-based immunotherapy for the treatment of cancer and a growing number of cancer patients in this region. For instance; according to the American Cancer Society, in 2020 there were 1.8 million cases of cancer diagnosed and 6, 06,520 cancer deaths in the United States. As NK cells can induce an antigen-independent immune response against malignant cells that are cancerous cells and also many clinical studies show promising anti-tumor effects when using NK cell-based immunotherapy. Therefore there is a rise in demand for NK cell-based immunotherapy. In addition, presence of key players and a rising number of product offerings in this region. For example; in April 2021 NKGen BIOTECH launched its product SNK-01. It is an autologous NK cells immunotherapy used for treating cancer.
Asia-pacific is expected to witness to grow with the highest CAGR in this market within the forecast period owing to the increasing demand for NK cells therapeutics to treat cancer. For example; according to National Cancer Registry 2020 in India, cancer cases in men are estimated to be 6,79,421 while among women it was estimated to be 712,758.
Report Analysis | Details |
---|---|
Historical data | 2015 - 2020 |
Forecast Period | 2021 - 2027 |
Market Size in 2020: | USD 1.94 Billion |
Base year considered | 2020 |
Forecast Period CAGR %: |
17.28 % |
Market Size Expected in 2027: | USD 5.92 Billion |
Tables, Charts & Figures: | 175 |
Pages | 200 |
NK Cell Therapy Companies: | Affimed, AltorBioscience Corporation, Celgene, CytoVac, Dynavax, GamidaCell, NantKwest, PersonGen BioTherapeutics, Surface Oncology, ZIOPHARM Oncology, Five Prime Therapeutics Nohla Therapeutics, iCell Gene Therapeutics, Fortress Biotech, Avid Biotic Corporation, Sorrento Therapeutics, Multimmune GmbH, Innate Pharma and others |
Segments Covered | By Type, By Diseases, By End-Users |
Regional Analysis | North America, U.S., Mexico, Canada, Europe, UK, France, Germany, Italy, Asia Pacific, China, Japan, India, Southeast Asia, South America, Brazil, Argentina, Columbia, The Middle East and Africa, GCC, Africa, Rest of the Middle East and Africa |
North America
Europe
Asia-Pacific
Latin America
Middle East and Africa
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