Gene Synthesis Market

Gene Synthesis Market Size, Share & Trends Analysis Report

Gene Synthesis Market Size By Component ( Product, Services), By Application(Research And Development, Diagnosis, Therapeutics) Forecast To 2027

Report ID : BMRC 1238
Number of pages : 300
Published Date : Nov 2022
Category : Healthcare
Delivery Timeline : 48 hrs


Gene Synthesis Market is valued at USD 3.14 Billion in 2018 and expected to reach USD 17.5 Billion by 2025 with the CAGR of 27.9% over the forecast period.

Increasing prevalence of cancer disease and rising demand of personalized medicine driving the gene synthesis market.  

Scope of Gene Synthesis Market-

Gene synthesis also refers as the artificial gene synthesis. Gene synthesis is described as the group of methods involves into the synthetic biology to construct and assemble gene from nucleotides. Unlike DNA synthesis in living cells, gene synthesis does not require template DNA. Gene synthesis involves two key steps, among them, the first step is solid phase DNA synthesis also known as 'DNA printing' that produces oligonucleotide fragments which are generally under 200 base pairs. The next step then involves connecting oligonucleotide fragments using multiple DNA assembly methods. Since gene synthesis does not need template DNA, this make possible to synthesis a completely synthetic DNA molecules with no limits on the nucleotide sequence or size.

Gene synthesis has multiple advantages including, it is used generate mutated, recombinant and completely novel DNA sequences without use of template. A wide variety of types of sequences can be produced which aid in research applications. Moreover, along with DNA sequences, RNA & oligos containing modified bases, chimeric DNA-RNA backbones can also be synthesized. In the era of gene synthesis, 2003 was the milestone as, the first synthesis of an entire viral genome, that of phiX174 bacteriophage is successfully completed.

Gene synthesis market report is segmented based on method, type, component, application and by regional & country level. Based upon method, gene synthesis market is classified into oligonucleotides and gene assembly. Based upon type, gene synthesis market is classified into gene library synthesis and custom gene synthesis. Based upon component, gene synthesis market is classified into product and services. Based upon application, gene synthesis market is classified into research and development, diagnosis, therapeutic and others.

The regions covered in this gene synthesis market report are North America, Europe, Asia-Pacific and Rest of the World. On the basis of country level, market of gene synthesis is sub divided into U.S., Mexico, Canada, U.K., France, Germany, Italy, China, Japan, India, South East Asia, GCC, Africa, etc.

Gene Synthesis Companies:

Gene synthesis market report covers prominent players like,

Thermo Genewiz

Eurofins Scientific

Quintara Biosciences

ATD Bio Ltd.

Fisher Scientific, Inc.

OriGene Technologies, Inc

Bioneer Corporation


Integrated DNA Technologies, Inc.

BioCat GmbH



Twist Bioscience.

LGC Biosearch Technologies

Eton Bioscience, Inc.

Bio Basic Inc.

SBS Genetech Co., Ltd.

Merck KGaA


Gene Synthesis Market Dynamics –

Increasing research and development in the field of genomics and next-generation sequencing is driving the growth of gene synthesis market. Additionally, increased government funding toward genomics, and rising demand for personalized medicine is expected to boost the growth of market over the forecast period. For instance, since personalized medicine provide tailor-made therapies to individual patients, depending on the molecular basis of disease, this therapy has become popular over recent years, for instance, as per the report of 2015, around 73 percent of total cancer drugs in development were based upon personalized therapy. Moreover, advancement of technology in healthcare, genomics, connected devices, big data analytics, and artificial intelligence are generating vast amounts of health data and insights enabling healthcare providers to offer better and faster diagnoses by making the use genome data. On the other flip, gene synthesis is involving critical technology that requires high cost to install, this may restrain the growth of market. Nevertheless, increasing incidence of cancer, subsequently personalized medicines are expected to create bunch of opportunities over the forecast period.

Gene Synthesis Market Regional Analysis –

North America is dominating the gene synthesis market followed by Europe due to the rising awareness about the growing prevalence of gene-related disorder. For instance, as per the National Cancer Institute (NCI), in 2016, around 1 million cancer cases were diagnosed in the in the U.S.A. Moreover, increased healthcare infrastructure and spend on health in the region fuelling the growth of market, for instance, as per the data of American Health Care, in the year of 2017, the United States spent around USD 3.5 trillion, or 18 percent of total GDP, on health expenditures.

Asia Pacific is anticipated to grow at a highest CAGR over forecast period due to positive trends associated with rising number of biopharmaceutical establishments and biotechnology companies, growing investments made by companies and government in gene synthesis research. For instance, Japan has a large number of companies those are involved in synthetic biology and gene synthesis. Furthermore, Rapid technological development in China and India is expected to attract global players for investments to develop gene synthesis technology in the Asia Pacific region will also bolster the market growth over the forecast period.

Key Benefits for Gene Synthesis Market Reports –

Global Market report covers in depth historical and forecast analysis.

Global Market research report provides detail information about Market Introduction, Market Summary, Global market Revenue (Revenue USD), Market Drivers, Market Restraints, Market opportunities, Competitive Analysis, Regional and Country Level.

Global Market report helps to identify opportunities in market place.

Global Market report covers extensive analysis of emerging trends and competitive landscape.

Gene Synthesis Market Segmentation –

By Method

  • Oligonucleotides
    • Phosphoramidite Reaction Cycle
    • High-Throughput Array-Based Gene Synthesis Technology
    • Ion Semiconductor Sequencing
    • Nanopore Sequencing
  • Gene Assembly
    • Polymerase-Based
      • Dual-Asymmetric (DA) PCR
      • Overlap Extension (OE)
      • Polymerase Cycling Assembly
      • Thermodynamically-Balanced Inside-Out (TBIO)
      • Microchip-Based Multiplex Gene Synthesis
      • Others
    • Ligase-Based
      • Shotgun Ligation
      • Two-Step Ligation and PCR
      • Ligase Chain Reaction
      • Brick-Based
    • Recombinant-Based
      • Sequence and Ligation Independent Cloning (SLIC)
      • Transformation-Associated Recombination
      • BioBrick Assembly

By Type

  • Gene Library Synthesis
  • Custom Gene Synthesis
    • cDNA
    • Customized Coding Sequences
    • Genomic DNA
    • RNAi Constructs
    • Others

By Component

  • Product
  • Services

By Application

  • Research and Development
  • Diagnosis
  • Therapeutics
  • Others

North America

  • U.S.
  • Canada


  • Germany
  • France
  • U.K.
  • Italy
  • Spain
  • Sweden
  • Netherland
  • Turkey
  • Switzerland
  • Belgium
  • Rest of Europe


  • South Korea
  • Japan
  • China
  • India
  • Australia
  • Philippines
  • Singapore
  • Malaysia
  • Thailand
  • Indonesia
  • Rest Of APAC

Latin America

  • Mexico
  • Colombia
  • Brazil
  • Argentina
  • Peru
  • Rest of South America

Middle East and Africa

  • Saudi Arabia
  • UAE
  • Egypt
  • South Africa
  • Rest Of MEA