Bispecific antibody is an artificial protein that is composed of fragments of two different monoclonal antibodies and has ability to bind to two different types of antigen. Cancer immunotherapy is the most widely explored application of bispecific antibody. Most of the bispecific antibodies are being developed for the treatment of multiple cancers followed by infectious disease, CNS disorders, inflammatory and autoimmune disorders. The benefits of bispecific antibodies over monoclonal therapeutics are due to their higher binding avidity to targets, which can interact with more than one surface antigen and boosted cytotoxic effects. It is because of the direct recruitment of effector cells to the site of the disease or in tumorigenic conditions. Bispecific antibodies may be used to improve clinical efficacy by targeting two disease mechanisms for the treatment of complex human diseases in a single agent. Bispecific antibodies also hold promise for certain therapeutic applications difficult to achieve by single-targeting monospecific antibodies, such as immune cell retargeting, site-specific targeting, enabling therapeutics to cross the blood–brain barrier, and unique receptor modulation.
Increasing research and development for novel bispecific antibodies is one of the major factors driving the Global Bispecific Antibodies Market.
"Global Bispecific Antibody market is valued at USD 457.5 Million in 2018 and expected to reach USD 697.5 Million by 2025 with the CAGR of 6.21% over the forecast period."
Aspen Pharmacare Holdings Limited is a multinational South African holding company established in 1850 and headquartered at Bldg Number 8 Healthcare Park Woodlands Dr Woodmead, Johannesburg, 2052, South Africa. Specialties in Branded, OTC, Consumer Health, Anaesthetics, Thrombosis, Injectables, Oral Solid Dose, Liquids, Semi-solids, Steriles, Biologicals, and API. Aspen Pharmacare Holdings had nearly 9454 Employees and had revenue of $2 Billion.
Bayer AG is a German multinational pharmaceutical and life sciences company Established in 1863 and headquartered at Kaiser-Wilhelm-Allee 1, Leverkusen, Nordrhein-Westfalen, 51373, Germany. Specialties in Pharmaceuticals , Consumer Health, Crop Science, Animal Health, Life Sciences, Research, Innovation, Sustainability, Health Care, Digital Farming, Food Security, Science For A Better Life, and Life sciences. Bayer had nearly 99,538 Employees and had revenue of $49 Billion.
C.H. Boehringer Sohn AG & Ko. KG is the parent company established in 1885 and headquartered at Binger Strasse 173, Ingelheim am Rhein, Rheinland-Pfalz, Germany. Specialties in Pharmaceuticals, Animal Health, Innovation, Research, Health Care, Improve Health, Biopharmaceuticals, and Contract Manufacturing. Boehringer Ingelheim had nearly 50,000 Employees and had revenue of $22 Billion.
Bristol Myers Squibb is an American multinational pharmaceutical company Established in 1887 and headquartered at 430 E 29th St 14th Floor, New York City, New York, 10016, United States. Specialties in biotechnology, innovation, great place to work, pharmaceuticals, research and development, and healthcare. Bristol-Myers Squibb had nearly 30,250 Employees and had revenue of $42 Billion.
Daiichi Sankyo Company, Limited is a global pharmaceutical company established in 2005 and headquartered at Nihonbashi-honcho, Chuo-ku, Tokyo, Tokyo, Japan. Specialties in therapies in hypertension, thrombotic disorders, stroke risk reduction, dyslipidemia, diabetes, acute coronary syndrome, opioid-induced constipation, IV iron therapy and metastatic melanoma. Daiichi Sankyo, Inc had nearly 15,348 Employees and had revenue of $9 Billion.
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