Safety & Prefilled Syringe Market

Safety & Prefilled Syringe Market Size, Share & Trends Analysis Report

Safety & Prefilled Syringe Market Size Share Companies & Trends Analysis Report By Product Type (Retractable Safety Syringe, Non-Retractable Safety Syringe), By Application (Insulin, Others), By End-User (Hospitals, Others), Based On Region And Segment Forecasts 2022 - 2028

Report ID : BMRC 1523
Number of pages : 300
Published Date : Nov 2022
Category : Medical Device
Delivery Timeline : 48 hrs
Single User : $3250

Corporate User : $7999

Safety & Prefilled Syringe Market is valued at  USD 1139.6 Million in 2020 and is expected to reach USD 2633.4 Million in 2027 with a CAGR of 8.95% over the forecast period. The safety & Prefilled Syringe market is expected to grow at significant growth rate due to number of driving factors.

Scope of the Global Safety & Prefilled Syringe Market Report: 

Syringes are the devices used to inject fluids into or withdraw them from something. It is usually operated by a piston pump system, which is an important method of medical treatment for patients by doctors or nurse staff. Safety & Prefilled Syringes are one of the types of the syringes used to package injectable drugs and diluents. Prefilled Syringes are single-dose packet of vaccine with fixed needle and have high level of accuracy. These are safe and disposable which are used to transport the vaccines where the exact dose is need as well as help in preventing the chances of overdosing. Some of the categories of drugs packaged in Prefilled Syringes are blood stimulants, therapeutic proteins, vaccines, erythron proteins, interferons, and rheumatoid arthritis. In Prefilled Syringes, the most used therapeutic categories are anaphylaxis, hematopoietic, anticoagulants, antivirals, monoclonal antibodies and vaccines. Prefilled Syringes have become a primary choice for most of the high-end injectable drugs due to the numerous advantages they offer over traditional packaging systems. These syringes offer various advantages like negligible overfill requirements, accurate drug dosing, ease of use and handling, increased assurance of sterility and time saved in emergency situations. In the earlier period, glass and metal syringes were widespread but progressively there has been a movement in the direction of plastic and safety and pre-filled syringes so that the needle is safe and protected and cannot be re-used which are Prefilled disposable systems. Thus, demand for appropriate and safe Prefilled Syringes in the medical field is increasing.



COVID-19 has positive impact on global safety & Prefilled Syringe market as growing production of Prefilled Syringes, supply chain reshaping and directly rise in demand, negative impact during coronavirus. The pharmaceutical packaging industry has observed a significant effect due to the COVID-19 outbreak. The increasing clinical trials for coronavirus vaccines had resulted in the high production of other related drugs for the treatments. For instance, in 2020, COVID-19 is reshaping the pharmaceutical supply chain in the medical emergency. The coronavirus pandemic may limit the safety & Prefilled Syringe markets where drugs are made for a clinical care. In addition, the change from conventional syringes to Prefilled Syringes due to the reduced risks of needle-stick injuries and infection will boost its production during coronavirus. For example, May 13, 2020, The US government had signed a deal of USD138 million with the makers of the syringe in order to facilitate the production of 100 million Prefilled Syringes by 2020 and more than 500 million Prefilled Syringes in 2021. Hence, leading companies in the safety & Prefilled Syringe market are taking advantage of on this trend and increasing their production capacities in order to prevent COVID-19.

The study provides a crucial view of Prefilled Syringe market by segmenting the market based on material, end-use and region & country level. Based upon material, Prefilled Syringe market is divided into polymer, and glass. Based upon end-use, Prefilled Syringe market is segmented as Pharmaceutical and Biopharmaceutical.

The study provides a crucial view of safety syringe market by segmenting the market based on product type, application, end-use and region & country level. Based upon product type, safety syringe market is divided into Retractable Safety Syringe and Non-Retractable Safety Syringe. Based upon application, safety syringe market is segmented into insulin and others. Based upon end-user, safety syringe market is segmented as hospitals and others.

Market Dynamics

Increasing healthcare expenditure, increasing prevalence of the various chronic diseases such as diabetes, cancer, hormonal diseases and others and growing adoption of self-care devices are some of the major factors driving the growth of the market. Increasing prevalence of the various chronic diseases such as diabetes is also stimulating the growth of the safety & Prefilled Syringe market. For instance; according to Diabetes Research and Clinical Practice is an international journal 2019, the global diabetes prevalence was 9.3% (463 million people) in 2019 and the number is escalating to 25% in 2030 and by 2045, the number is projected to increase by 51%. One in two people living with diabetes which is leading to grow the safety of the patient by taking insulin with syringes while Prefilled Syringes are the safest manner. Thus, increasing prevalence of the various chronic diseases such as diabetes is driving the growth of safety & Prefilled Syringe market.


Report Analysis Details
Historical data 2018 - 2021
Forecast Period 2022 - 2028
Market Size in 2020: USD 1139.6 Million
Base year considered 2021
Forecast Period CAGR %:

8.95 %

Market Size Expected in 2027: USD 2633.4 Million
Tables, Charts & Figures: 175
Pages 200
Key Players/Companies Becton, Dickinson and Company,Cardinal Health, Inc,Retractable Technologies, Inc.,Wuxi Yushou Medical Devices Co., Ltd.,Shanghai Mishawa Medical Industry Co., Ltd.,Others
Segments Covered By Product Type, By Application, By End User
Regional Analysis North America, U.S., Mexico, Canada, Europe, UK, France, Germany, Italy, Asia Pacific, China, Japan, India, Southeast Asia, South America, Brazil, Argentina, Columbia, The Middle East and Africa, GCC, Africa, Rest of the Middle East and Africa


In addition, high demand for improved safety injectables, rising demand and higher production of large molecule biologics and biosimilar are also supplementing the market growth. Furthermore, increasing number of product offerings are also augmenting the growth of the global safety & Prefilled Syringe market. For instance; W. L. Gore & Associates, Inc., an American multinational manufacturing and global materials science company commercially launched GORE ImproJect Plunger for pre-filled syringes in 2019. The pre-filled syringe systems use silicone to act as a lubricant between the barrel and the plunger as well as to help deliver a seal. Also, Temuro Medical Corporation launched PLAJEX silicone oil-free Prefilled Syringe in 2019 which provides treatment option for patients. However, the availability of innovative, better and effective alternative such as nano-patches and other non-invasive methods may limit the growth of the safety & Prefilled Syringe market. In spite of that, compared to existing Prefilled Syringes, industry participants are investing more and more in the research and development of new and more powerful chemicals, which can create market opportunities within the forecast period.

The material segment of the global pre-filled syringe market is dominated by Glass with the largest market share of 80.66% in 2020. The end-user segment of global pre-filled syringe is dominated by Pharmaceutical with the largest share of 79.35% in the year 2020.

The product Type segment of the global safety syringe market is dominated by Retractable Safety Syringe with the largest market share of 70.59% in 2020. The application segment of the global safety syringe market is dominated by insulin with the largest market share of 81.13% in 2020. The end-user segment of global safety syringe is dominated by hospitals with the largest share of 86.98%in the year 2020.

Safety & Prefilled Syringe Market Segmentation:

By Product Type

  • Retractable Safety Syringe
  • Non-Retractable Safety Syringe

By Application

  • Insulin
  • Others

By End User

  • Hospitals
  • Others

Safety & Prefilled Syringe Market Key Players:

  • Becton, Dickinson and Company
  • Cardinal Health, Inc
  • Retractable Technologies, Inc.
  • Wuxi Yushou Medical Devices Co., Ltd.
  • Shanghai Mishawa Medical Industry Co., Ltd.
  • Others

Regional Analysis

North America is expected to dominate the global safety & Prefilled Syringe market due to the increasing healthcare expenditure and growing prevalence of chronic diseases into the region. For instance; according to the Centers for Disease Control and Prevention, U.S. Department of Health & Human Services 2020, the national expenditure per capital in Unites States in 2018 was $11,172 and the total national health expenditure was $3.6 trillion in 2018. Europe is one of the major revenue-generating regions in the global safety & Prefilled Syringe market. The demand for Prefilled Syringes has been increasing due to various factors such as rising demand for safety Prefilled Syringes, growth of the biologics and biosimilars market, technological advancements and high adoption of self-injection devices in this region. For example; according to the European Federation of Pharmaceutical Industries and Associations 2019, R&D investment scoreboard pharmaceutical and biotechnology sector amounts to 18.9% of total business R&D expenditure across the globe. Several pharmaceutical companies like Gerresheimer AG, Schott Group, Vetter Pharma and other are investing in production in R&D expenditures.

Market Trends

The safety & Prefilled Syringes are the syringes which are filled at the time of manufacturing and packaging instead of drug administration. Most of the time products come in glass vessel or ampoule & it is withdrawn into syringe when administration is required and then injected in patient. To avoid lack of convenience, accuracy, affordability, safety, sterility, etc., these Prefilled Syringes are now used. These syringes are used to deliver parenteral medications and are single dose packet of parenteral drug in which a needle is fixed by a manufacturer. These Prefilled Syringes are ready to use disposable syringes that contain premeasured dosage to reduce dosing errors and increase dosing accuracy, patient compliance, convenience and safety, also to enhance patient quality of life & reduce patient time in the clinic. They are more convenient devices for the delivery of parenteral medications. They are small in size which makes them easy to carry and are dependable for delivering a precise dose of medication. Prefilled Syringes provide various advantages for the manufacturer, physician and patient over conventional method of parenteral drug delivery. Some of these advantages are such as accuracy, sterility, convenience, affordability and safety.

Some of the Major Trends of the Global Safety & Prefilled Syringe Market are:


Pre-filled safety syringes are not only safer than those without needle protection but are also more convenient and they are well-adapted to the self-administration trend. In particular, retracting needle mechanisms used in pre-filled safety syringes and auto-injectors allow both ease-of-use and safety device requirements to be met all at once, while also potentially reducing the risk of dosage errors. By allowing older, weakened and less-dextrous patients to securely hold & operate the device without any assistance, these instruments contribute for providing patients with the independence that comes with self-administration, whereas for reducing the risks associated with unsupervised self-care.

COP Prefilled Syringes:

The material used for the safety & Prefilled Syringes is a high performance polymer called Cyclic Olefin Polymer (COP). It is suitable for use as a primary packaging for sophisticated medications, especially for biosimilars, sensitive biologicals and biobetters, but also for e.g. hyaluronic acid applications. These COP polymer syringes are widely used & these are distinguished by a high degree of break resistance and a glass-like transparency. COP discharges no alkali ions that mean that the risk of a pH value shift is eliminated. Subsequently the entire plastic syringes which include the insert-molded needle is produced in a single step, hence the polymer syringes become free of tungsten & adhesives. Its production with injection molding process enables flexible designs even customer-specific designs are possible. In comparison to glass, more precise production tolerances are possible with COP Prefilled Syringes. This makes a higher degree of customized solutions possible. For example; when a lower remaining volume is required, high-quality cyclic olefin polymers (COP) such as the Daikyo Crystal Zenith syringe systems are designed to overcome challenges of glass syringes and to add value to sensitive biologics. This includes the absence of silicone oil in Daikyo Crystal Zenith syringes & it results in decreased interaction with the drug product and enhanced cleanliness. These polymer syringes present attractive benefits that are gaining increased attention from manufacturers seeking new answers to the drug delivery and administration challenges. This is through break resistance, superior functional performance, highly reduced extractables and leachables, and the availability of many sterile formats.

Plajex – a Silicone Oil-Free Pre-Filled Syringe:

The PLAZX syringe is a barrel of a syringe used to be used as a medical medicine container. It is manufactured by Terumo Manufacturing only as an empty pre-fillable syringe component which will be processed by further pharmaceutical companies as per their filling requirements. This PLAX is a polymer pre-filament syringe specially formulated for the use of biopharmaceuticals. Its design and production method is also unique, using silicone oil free and autoclave disinfection. This contributes to the reduction of risks such as aggregation and oxidation of biopharmaceuticals. This device is designed to meet the needs of a wide variety of drugs requiring low reactive containers. It provides low feedback in Cyclo olefin polymer (COP) with 1 mL long, stacked needle with low sub-visible particles, proteins, excellent strength and clarity, and can be sterilized for ready-filled nest presentation. It is a ready-to-fill format, silicone oil free, tungsten free, glue free, high resistance to breaks and autoclave advantage.

Dual Chamber Prefilled Syringes:

The dual chamber Prefilled Syringe is used to store a large amount of organic matter or active medicinal ingredients that may not be stable for extended periods of time. This syringe enables to prevent drug damage by maintaining drug sterility before injection. Advances in technology have improved the arrangement of liquid components in syringes and injectors, and patients are more attracted to choose a safer and more efficient syringe. These prefill dual chamber syringe devices can improve long-term (bio) pharmaceutical stability by storing them in freeze-dried form before administration and are therefore becoming more popular for those volatile (bio) pharmaceutical products. It is glue-free to eliminate the risk of interaction with drug products and cannot be reused which makes it safe to dispose of. The development of DCDs for drug and flush solutions instead of catheters seems to be an important step in facilitating better clinical practices in many hospitals. Catheters prevent patient complications such as phlebitis or infection and make it easier for medical staff.

On Special Requirement Safety & Prefilled Syringe Market Report is also available for below Regions and Country:

North America

  • U.S.
  • Canada


  • Germany
  • France
  • U.K.
  • Italy
  • Spain
  • Sweden
  • Netherland
  • Turkey
  • Switzerland
  • Belgium
  • Rest of Europe


  • South Korea
  • Japan
  • China
  • India
  • Australia
  • Philippines
  • Singapore
  • Malaysia
  • Thailand
  • Indonesia
  • Rest Of APAC

Latin America

  • Mexico
  • Colombia
  • Brazil
  • Argentina
  • Peru
  • Rest of South America

Middle East and Africa

  • Saudi Arabia
  • UAE
  • Egypt
  • South Africa
  • Rest Of MEA

Key Benefits for Global Safety & Prefilled Syringe Market Report:

  • Global Safety & Prefilled Syringe market report covers in-depth historical and forecast analysis.
  • Global Safety & Prefilled Syringe market research report provides detail information about Market Introduction, Market Summary, Global market Revenue (Revenue USD), Market Drivers, Market Restraints, Market Opportunities, Competitive Analysis, Regional and Country Level.
  • Global Safety & Prefilled Syringe market report helps to identify opportunities in marketplace.
  • Global Safety & Prefilled Syringe market report covers extensive analysis of emerging trends and competitive landscape.
Vishal Sawant
Busines Development
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